Hoi-Ying Holman is a scientist in both the Climate and Ecosystem Sciences Division of Berkeley Lab’s Earth and Environmental Sciences Area (EESA) and in the Molecular Biophysics and Integrated Bioimaging (BMIB) Division of Berkeley Lab’s Biological Sciences Area. She received her PhD from University of California at Berkeley. Her research interests are in microbial ecology, geomicrobiology, bioenergy, bioremediation, and bioavailability of chemicals to ecological receptors. As a Director of the Berkeley Synchrotron Infrared Structural Biology (BSISB) imaging program at the Advanced Light Source (ALS), she focuses on developing and providing research communities new synchrotron infrared (SIR) technologies for deciphering the relationship between genome and functional processes, and identifying the connection between the genome and natural environments. She and her team, Drs. Sun Choi, Liang Chen, and Giovanni Birarda, were awarded a 2014 R&D 100 award for their development of the Berkeley Lab Multiplex Chemotyping Microarray (MCM). Current technologies in active development in the BSISB program are: SIR nano-spectroscopy, SIR plasmon resonance microscopy, and the integration of SIR spectromicroscopy with ambient IR laser ablation (AIRLAB) mass spectrometry.